FitoslimÒ - FAQ's

What is FitoslimÒ Starch NeutralizerÔ

FitoslimÒ

is an amazing, non-stimulant, all-natural

nutritional ingredient that is derived from the white

kidney bean. It is the first nutritional ingredient that

has been clinically & scientifically proven to

neutralize starch, found in your favorite foods such as

potatoes, breads, pasta. rice, corn and crackers.

FitoslimÒ is a safe yet powerful nutritional ingredient,

clinically studied to reduce the absorption of starch

calories.

FitoslimÒ allows you to enjoy those foods that you love

without all the calories.

How does FitoslimÒ work?

During the digestive process, your body converts

carbohydrates, found in starchy foods such as potatoes

and pasta, into sugar. Your body does this by

breaking-down the carbohydrate molecules with alpha

amylase, an enzyme that is produced in the pancreas.

These sugar calories are either burned off, through

exercise, or stored as fat cells for future use.

Unfortunately, inactivity means that these stored fat

cells accumulate. The result is weight gain.

When should I take FitoslimÒ?

Recent research has shown the most optimum time to

take FitoslimÒ is just before a starch-rich meal along

with 8 oz of water. However, the studies also showed

that FitoslimÒ could still provide some of its starch

"neutralizing" benefits when taken during, or just

after, a starch-rich meal. One such study demonstrated

that FitoslimÒ

could remain effective when a capsule is

opened and sprinkled onto food.

Does Fitoslim® cause any toxic side effects?

A dose equivalent to 74 grams taken daily for 90 days by

a 165 lb. person showed no signs of toxicity. Pharmachem

Laboratories Inc., announced that a Chronic Toxicity

Study (L.D.50) demonstrated that FitoslimÒ Starch

Neutralizer™, the first standardized white bean extract

used in a variety of weight loss supplements, is safe

and non-toxic.

FitoslimÒ showed no signs of chronic toxicity at

doses up to 1.0 gm/kg body weight for up to 90 days,”

said Ramadasan Kuttan, Ph.D., director, Amala Cancer Research

Center, Thrissur, India, who conducted the study along

with R. C. Srimal, M.D. “The data indicates that

administration of for 90 days did not produce

any adverse reaction as seen from the organ weight,

necropsy, haematological values and biochemical values.”

Are there any human studies that prove FitoslimÒ effectiveness?

Yes. Human studies indicate that this natural starch

blocker has the ability to inhibit starches found in

foods from being broken down to simple sugar. This

amylase inhibiting effect causes most starches to pass

through the GI tract undigested thus causing a smaller

increase in blood glucose levels within 15 to 80 minutes

following intake of starchy carbohydrate foods. The

following describes one of the studies performed on

FitoslimÒ,

November 20 - In vivo effectiveness of a starch

absorption blocker in a double-blind placebo-controlled

study with normal college-age subjects.

Joe A. Vinson, PhD and Donna M. Shuta, BS

Department of Chemistry

University of Scranton

Scranton, PA 18510

Inhibition of carbohydrate metabolism or absorption is

one mechanism to reduce hyperglycemia in normal and

especially in diabetic subjects. Another possible

benefit is the decrease in calorie intake after eating

carbohydrates for obesity and weight loss. In the 1980's

there were several reports of in vitro and in vivo

effectiveness of a natural starch blocker that worked by

inactivating the enzyme amylase. We investigated this

hypothesis with an initial pilot study. After this

initial study with subjects who were physically active

during the study, we did a second study to confirm the

results. In this second study, again there was a

double-blind placebo-controlled crossover trial with ten

subjects (five males and five females aged 21 to 27) who

participated with informed consent. After an overnight

fast the subjects appeared in the morning and were given

in a random fashion either

1. placebo consisting of 4 slices of white bread (60 g of

carbohydrate), 42 g of soybean oil margarine, and 4 g

of Sweet N'Low

experimental comprising the control plus 1.5 g of

2. FitoslimÒ (Pharmachem Laboratories).

The subjects rested between blood drawings. Plasma

glucose was measured from blood sample drawn at baseline

and every 15 minutes for 1 hour, then every 20 minutes

for the second hour. Two subjects did not complete the

study and 4 subjects were poor/non-absorbers as the area

under the glucose-time curve was negative. Therefore the

data of the remaining 4 subjects was used.

As expected the control bread produced an increase in

glucose in the normal subjects that reached a broad peak

after 45 minutes. The peak glucose for the FitoslimÒ

group occurred at 30 minutes. This dose of FitoslimÒ

produced a smaller increase than the control from 15 to

80 minutes, with an almost significant difference (p <

0.1) at 45 and 60 minutes. The glucose cleared from the

plasma about 30 minutes earlier with the Phaseolamin™

compared to the control. The area under the plasma

glucose-time curve (a measure of glucose absorption and

metabolism) was 85% lower with the FitoslimÒ, p < 0.05.

Thus only 15% of the glucose in the bread compared to

the control found its way into the body in the presence

of FitoslimÒ. These results show the effectiveness of the

product in decreasing the absorption of glucose from

complex carbohydrates from this group of subjects.